Psychiatry Research
Volume 153, Issue 2 , Pages 171-177, 31 October 2007

Symptoms of neurasthenia following earthquake trauma: Re-examination of a discarded syndrome

  • Wei Zhang

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
    • Corresponding Author InformationCorresponding author. Duke University Medical Center, Department of Psychiatry and Behavioral Sciences, Box 3812, Durham, NC 27710, USA. Tel.: +919 684 5645; fax: +919 684 8866.
  • ,
  • Li-Ching Lee

      Affiliations

    • Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
  • ,
  • Kathryn M. Connor

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
  • ,
  • Chia-Ming Chang

      Affiliations

    • Institute of Medicine, Chung Shan Medical University and Department of Psychiatry, Chung Shan Medical Hospital, Taichung, Taiwan
  • ,
  • Te-Jen Lai

      Affiliations

    • Institute of Medicine, Chung Shan Medical University and Department of Psychiatry, Chung Shan Medical Hospital, Taichung, Taiwan
  • ,
  • Jonathan R.T. Davidson

      Affiliations

    • Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA

Received 26 April 2005; received in revised form 14 November 2005; accepted 21 April 2006.

Abstract 

The authors examined symptoms of neurasthenia in the context of trauma through a survey conducted 10 months post-earthquake, among a sample of earthquake survivors in rural Taiwan. An algorithm closely resembling neurasthenia as defined in ICD-10 was designed a priori. Three diagnostic groups were identified, including those with “pure” neurasthenia (n=27) who did not exhibit any Axis I disorder, those with an Axis I disorder but without neurasthenia (n=46) and controls who were without neurasthenia or an Axis I disorder (n=152). Those with neurasthenia were demographically similar to non-psychiatrically disordered controls and did not differ with respect to impact of trauma. Greater severity of intrusive and avoidant/numbing posttraumatic stress disorder (PTSD) symptoms and less resilience characterized neurasthenia relative to controls. Morbidity was similar for neurasthenia and Axis I disorders, except for the presence of less resilience in the neurasthenia group. Thus, “pure” neurasthenia appears to be independent from other psychopathology in a significant number of earthquake survivors, and was not closely related to the impact of earthquake trauma. The meaningful number of subjects meeting criteria for our algorithm of neurasthenia suggests that further study of this syndrome employing exact ICD-10 diagnostic criteria is warranted.

Keywords: Posttraumatic stress disorder, Somatization, Prevalence, Disability

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PII: S0165-1781(06)00122-3

doi:10.1016/j.psychres.2006.04.021

Psychiatry Research
Volume 153, Issue 2 , Pages 171-177, 31 October 2007