CD24 gene polymorphism is associated with the disease progression and susceptibility to multiple sclerosis in the Iranian population

Received 5 June 2008; received in revised form 18 November 2008; accepted 5 January 2009.

Abstract

The impact of a single nucleotide polymorphism (SNP) in the CD24 gene on the risk and progression of multiple sclerosis (MS) was investigated in the Iranian population. Our data revealed that the susceptibility and the progression of MS in individuals with the CD24V/V genotype were greater than in those with the CD24A/V and CD24A/A genotypes.

Keywords: Single nucleotide polymorphism, Multiple sclerosis, Iranian population

Division of Genetics, Department of Biology, Faculty of Science, The University of Isfahan, Isfahan, Iran

Corresponding author. Tel./fax: +98 311 7932456.

PII: S0165-1781(09)00014-6

doi:10.1016/j.psychres.2009.01.002

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