Early and delayed personality changes associated with depression recovery? a one-year follow-up study

Corruble, Emmanuelle; Duret, Caroline; Pelissolo, Antoine; Falissard, Bruno; Guelfi, Julien Daniel

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Volume 109, Issue 1 , Pages 17-25, 31 January 2002

Early and delayed personality changes associated with depression recovery? a one-year follow-up study

Emmanuelle Corruble
- Psychiatry Department, Paul Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Paris XI University, 12 Avenue P.V. Couturier, F-94804 Villejuif Cedex, France
- Corresponding author. Tel.: +33-1455-930-87; fax: +33-1455-934-24
Caroline Duret
- Psychiatry Department, Paul Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Paris XI University, 12 Avenue P.V. Couturier, F-94804 Villejuif Cedex, France
Antoine Pelissolo
- Psychiatry Department, Fernand Widal Hospital, Assistance Publique-Hôpitaux de Paris, Paris VII University, Paris, France
Bruno Falissard
- Biostatistics Department, Paul Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Paris XI University, Villejuif, France
Julien Daniel Guelfi
- Psychiatry Department, Paul Brousse Hospital, Assistance Publique-Hôpitaux de Paris, Paris XI University, 12 Avenue P.V. Couturier, F-94804 Villejuif Cedex, France

Received 22 January 2001; received in revised form 3 August 2001; accepted 19 August 2001.

Abstract

Many studies have shown the state effect of depression on personality. However, the chronology of personality changes associated with depression recovery remains unstudied. The objective of this study is to assess early (first month) and delayed personality changes associated with depression recovery. Fifty-seven depressed inpatients were assessed with the Temperament and Character Inventory (TCI) at admission, 1 month, and 1 year post-treatment. Patients were divided into poor and favorable outcome. No significant personality change was observed in patients with poor depression outcome. Conversely, a favorable outcome of depression was associated with early and delayed personality changes. Early changes were: decrease in Harm avoidance (HA₁:Worry and pessimism), increase in Cooperativeness and Self-directedness (SD₁:Responsibility, SD₄:Self-acceptance, SD₂:Purposefulness and SD₃:Resourcefulness). Delayed changes were changes in character: increase in Self-Directedness (SD₁:Responsibility, SD₄:Self-acceptance, SD₅: Congruent second nature), decrease in Self-transcendence (ST₂:Transpersonal identification). This study shows the different status of personality changes associated with depression recovery, and it contributes to a better knowledge of the state effect and of subtle clinical changes in patients who are recovering from depression. It may also have implications for the prediction of depression outcome.