Psychiatry Research
Volume 109, Issue 2 , Pages 207-210 , 15 March 2002

Beta-thromboglobulin and platelet factor 4 levels in post-myocardial infarction patients with major depression

  • Petra M.J.C. Kuijpers

      Affiliations

    • Department of Psychiatry, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands
    • ,
  • Karly Hamulyak

      Affiliations

    • Department of Hematology, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands
    • ,
  • Jacqueline J.M.H. Strik

      Affiliations

    • Department of Psychiatry, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands
    • ,
  • Hein J.J. Wellens

      Affiliations

    • Interuniversity Cardiological Institute Netherlands, P.O. Box 19258, 3501 DG Utrecht, The Netherlands
    • ,
  • Adriaan Honig

      Affiliations

    • Department of Psychiatry, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands
    • Corresponding Author InformationCorresponding author

Received 6 August 2001 ,Revised 2 January 2002 ,Accepted 21 January 2002.

References 

  1. Furman MI, Benoit SE, Barnards MR, Valeri CR, Borbone ML, Becker RC, et al. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. Journal of the American College of Cardiology. 1998;31:352–358
  2. Laghrissi-Thode F, Wagner WR, Pollock BG, Johnson PC, Finkel MS. Elevated platelet factor 4 and β-thromboglobulin plasma levels in depressed patients with ischemic heart disease. Biological Psychiatry. 1997;42:290–295
  3. Levine SP, Lindenfeld J, Ellis JB, Raymond NM, Krentz LS. Increased plasma concentrations of platelet factor 4 in coronary artery disease; a measure of in vivo platelet activation and secretion. Circulation. 1981;64:626–632
  4. Musselman DL, Marzec UM, Manatunga A, Penna S, Reemsnyder A, Knight BT, et al. Platelet reactivity in depressed patients treated with paroxetine. Archives of General Psychiatry. 2000;57:875–882
  5. Nemeroff CB, Musselman DL. Are platelets the link between depression and ischemic heart disease?. American Heart Journal. 2000;140:S57–S62
  6. Noble MIM, Drake-Holland AJ. The role of serotonin 5HT2 receptor antagonism in the control of coronary artery disease. Quarterly Journal of Medicine. 1994;87:11–16
  7. Pepper DS, Prowser CV. Beta-thromboglobulin and platelet factor 4. In:  Jespersen J,  Bertina RM,  Haverkate F editor. ECAT Assay Procedures; A Manual of Laboratory Techniques. Dordrecht: Kluwer Academic Publishers; 1998;
  8. Smitherman T, Milam , Woo , Willerson , Frenkel . Elevated beta thromboglobulin in peripheral venous blood of patients with acute myocardial ischemia: direct evidence for enhanced platelet reactivity in vivo. American Journal of Cardiology. 1981;48:395–402
  9. Serebruany VL, Gurbel PA, Shustov AR, Ohman EM, Topol EJ. Heterogeneity of platelet aggregation and major surface receptor expression in patients with acute myocardial infarction. American Heart Journal. 1998;136:398–405

PII: S0165-1781(02)00017-3

Psychiatry Research
Volume 109, Issue 2 , Pages 207-210 , 15 March 2002

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