Psychiatry Research
Volume 120, Issue 1 , Pages 29-35 , 30 August 2003

Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts

  • Laure Buydens-Branchey

      Affiliations

    • Department of Psychiatry, State University of New York-Health Science Center at Brooklyn and Veterans Affairs New York Harbor Healthcare System, Brooklyn Campus (11S/BK), 800 Poly Place, Brooklyn, NY 11209, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-718-836-6600x6129; fax: +1-718-630-2967
    • ,
  • Marc Branchey

      Affiliations

    • Department of Psychiatry, State University of New York-Health Science Center at Brooklyn and Veterans Affairs New York Harbor Healthcare System, Brooklyn Campus (11S/BK), 800 Poly Place, Brooklyn, NY 11209, USA
    • ,
  • Dana L. McMakin

      Affiliations

    • National Institute of Alcohol Abuse and Alcoholism, 12420 Parklawn Drive, Rockville, MD 20852, USA
    • ,
  • Joseph R. Hibbeln

      Affiliations

    • National Institute of Alcohol Abuse and Alcoholism, 12420 Parklawn Drive, Rockville, MD 20852, USA

Received 25 July 2002 ,Revised 25 April 2003 ,Accepted 28 May 2003.

References 

  1. Chalon S, Delion-Vancassel S, Belzung C, Guilloteau D, Leguisquet AM, Besnard JC, et al. Dietary fish oil affects monoaminergic neurotransmission and behavior in rats. Journal of Nutrition. 1998;128:2512–2519
  2. de la Pressa Owens S, Innis SM. Diverse, region-specific effects of addition of arachidonic and docosahexanoic acids to formula with low or adequate linoleic and α-linolenic acids on piglet brain monoaminergic neurotransmitters. Pediatric Research. 2000;48:125–130
  3. Delion S, Chalon S, Guilloteau D, Besnard JC, Durand G. α-Linolenic acid dietary deficiency alters age-related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex. Journal of Neurochemistry. 1996;66:1582–1591
  4. Delion S, Chalon S, Hérault J, Guilloteau D, Besnard JC, Durand G. Chronic dietary α-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats. Journal of Nutrition. 1994;124:2466–2476
  5. Gesch CB, Hammond SM, Hampton SE, Eves A, Crowder MJ. Influence of supplementary vitamins, minerals and essential fatty acids on the antisocial behavior of young adult prisoners. British Journal of Psychiatry. 2002;181:22–28
  6. Hibbeln JR, Linnoila M, Umhau C, Rawlings R, George DT, Salem N. Essential fatty acids predict metabolites of serotonin and dopamine in cerebrospinal fluid among healthy control subjects and early- and late-onset alcoholics. Biological Psychiatry. 1998;44:235–242
  7. Hibbeln JR, Salem N. N-3 fatty acids and psychiatric disorders. Current status of the field. In:  Mostofosky D,  Yehuda S,  Salem N editor. Fatty Acids: Physiological and Behavioral Functions. Totowa, NJ: Humana Press; 2001;p. 311–330
  8. Ingram SL, Amara SG. Arachidonic acid stimulates a novel cocaine-sensitive cation conductance associated with the human dopamine transporter. Journal of Neuroscience. 2000;20:550–557
  9. L'hirondel M, Cheramy A, Godeheu G, Glowinski J. Effects of arachidonic acid on dopamine synthesis, spontaneous release and uptake in striatal synaptosomes from the rat. Journal of Neurochemistry. 1995;64:1406–1409
  10. Lepage G, Roy CC. Specific methylation of plasma non-esterified fatty acids in a one-step reaction. Journal of Lipid Research. 1988;29:227–235
  11. Moriguchi T, Greiner RS, Salem N. Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration. Journal of Neurochemistry. 2000;75:2563–2573
  12. Nemets B, Stahl Z, Belmaker RH. Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder. American Journal of Psychiatry. 2002;159:477–479
  13. Olsson NU, Shoaf SE, Salem N. The effect of dietary polyunsaturated fatty acids and alcohol on neurotransmitters levels in rat brain. Nutritional Neuroscience. 1998;1:133–140
  14. Peet M, Horrobin D. A dose ranging study of the effects of ethyl ester eicosapentaenoate in patients with ongoing depression in spite of apparently adequate treatment with standard antidepressants. Archives of General Psychiatry. 2000;59:913–919
  15. Salem N, Litman B, Kim HY, Gawrisch K. Mechanisms of action of docosahexaenoic acid in the nervous system. Lipids. 2001;36:945–959
  16. Spitzer RL, Williams JB, Gibbon M, First MB. User's Guide for the Structured Clinical Interview of the DSM-III-R. Washington, DC: American Psychiatric Press; 1990;
  17. Stanley M, Mann JJ. Increased serotonin-2 binding sites in frontal cortex of suicide victims. Lancet. 1983;8318:214–216
  18. Wannasirindr, M., Itomura, M., Thienprasert, A., Hamazaki, T., 2000. Polyunsaturated fatty acids composition in heroin addicts. Presented at the 4th Congress of the International Society for the Study of Fatty Acids and Lipids, Tsukuba, Japan
  19. Yehuda S, Rabinovitz S, Mostofsky DI. Essential fatty acids are mediators of brain biochemistry and cognitive functions. Journal of Neuroscience Research. 1999;56:565–570
  20. Zhang L, Reith ME. Regulation of the functional activity of the human dopamine transporter by the arachidonic acid pathway. European Journal of Pharmacology. 1996;315:345–354
  21. Zimmer L, Delion-Vancassel S, Durand G, Guilloteau D, Bodard S, Besnard JC, et al. Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids. Journal of Lipid Research. 2000;41:32–40
  22. Zimmer L, Delpal S, Guilloteau D, Aı̈oun J, Durand G, Chalon S. Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex. Neuroscience Letters. 2000;284:25–28

PII: S0165-1781(03)00168-9

doi: 10.1016/S0165-1781(03)00168-9

Psychiatry Research
Volume 120, Issue 1 , Pages 29-35 , 30 August 2003

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