Psychiatry Research
Volume 129, Issue 1 , Pages 39-44 , 30 November 2004

Assessing publication bias in genetic association studies: evidence from a recent meta-analysis

  • Marcus R. Munafò

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44-1865-224807; fax: +44-1865-224989.
    • Department of Clinical Pharmacology, Cancer Research UK, General Practice Research Group, University of Oxford, Oxford OX2 6HE, UK
  • ,
  • Taane G. Clark

      Affiliations

    • Centre for Statistics in Medicine, Cancer Research UK, University of Oxford, Oxford OX3 7LF, UK
  • ,
  • Jonathan Flint

      Affiliations

    • Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK

Received 10 July 2003 ,Revised 12 June 2004 ,Accepted 14 June 2004.

References 

  1. Attia J, Thakkinstian A, D'Este C. Meta-analyses of molecular association studies: methodologic lessons for genetic epidemiology. Journal of Clinical Epidemiology. 2003;56:297–303
  2. Begg CB, Mazumdar M. Operating characteristics of rank correlation test for publication bias. Biometrics. 1994;50:1088–1101
  3. Dear KBG, Begg CB. An approach to assessing publication bias prior to performing a meta-analysis. Statistical Science. 1992;7:237–245
  4. Du L, Bakish D, Hrdina PD. Gender differences in association between serotonin transporter gene polymorphism and personality traits. Psychiatric Genetics. 2000;10:159–164
  5. Duval SJ, Tweedie RL. Trim and fill: a simple funnel plot based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56:455–463
  6. Duval SJ, Tweedie RL. A non-parametric “trim and fill” method of assessing publication bias in meta-analysis. Journal of the American Statistical Association. 2000;95:89–98
  7. Egger M, Davey-Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. British Medical Journal. 1997;315:629–634
  8. Egger M, Davey-Smith G, Altman D. Systematic Reviews in Healthcare. 2nd ed.. London: British Medical Journal Books; 2001;
  9. Gilbody SM, Song F. Publication bias and the integrity of psychiatry research. Psychological Medicine. 2000;30:253–258
  10. Hedges LV. Modeling publication selection effects in meta-analysis. Statistical Science. 1992;7:246–255
  11. Iyengar S, Greenhouse JB. Selection problems and the file drawer problem. Statistical Science. 1988;3:109–135
  12. Kluger AN, Siegfried Z, Ebstein RP. A meta-analysis of the association between DRD4 polymorphism and novelty seeking. Molecular Psychiatry. 2002;7:712–717
  13. Munafò MR, Clark TG, Moore LR, Payne E, Flint J. Genetic polymorphisms and personality in healthy adults: a systematic review and meta-analysis. Molecular Psychiatry. 2003;8:471–484
  14. Petticrew M, Gilbody SM, Sheldon TA. Relation between hostility and coronary heart disease. British Medical Journal. 1999;319:917–918
  15. Rosenthal R. The ‘file drawer problem’ and tolerance for null results. Psychological Bulletin. 1979;86:638–641
  16. Song F, Eastwood AJ, Gilbody S, Duley L, Sutton AJ. Publication and related biases. Health Technology Assessment. 2000;4:1–115
  17. Sterling TD. Publication decision and their possible effects on inferences drawn from tests of significance—or vice versa. Journal of the American Statistical Association. 1959;54:30–34
  18. Sterne JAC, Gavaghan D, Egger M. Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature. Journal of Clinical Epidemiology. 2000;53:1119–1129
  19. Sutton AJ, Duval SJ, Tweedie RL, Abrams KR, Jones DR. Empirical assessment of effect of publication bias on meta-analyses. British Medical Journal. 2000;320:1574–1577
  20. Vevea JL, Hedges LV. A general linear model for estimating effect size in the presence of publication bias. Psychometrika. 1995;60:419–435
  21. Wang MC, Bushman BJ. Using normal quantile plots to explore meta-analytic data sets. Psychological Methods. 1998;3:46–54
  22. Weisberg S, Bingham C. An approximate analysis of variance test for non-normality suitable for machine calculation. Technometrics. 1972;17:133–134

PII: S0165-1781(04)00168-4

doi: 10.1016/j.psychres.2004.06.011

Psychiatry Research
Volume 129, Issue 1 , Pages 39-44 , 30 November 2004