Psychiatry Research
Volume 129, Issue 2 , Pages 191-199, 15 December 2004

Neuropsychological subtyping of schizophrenia

Department of Psychiatry, Turku University Central Hospital, University of Turku, Kunnallissairaalantie 20, FIN-20520 Turku, Finland

Received 28 June 2002; received in revised form 10 July 2003; accepted 5 August 2003.

Abstract 

Schizophrenia tends to be associated with a general decline in cognitive functioning. However, some studies have found neuropsychologically normal schizophrenia patients. To address this contradiction, we screened first-episode schizophrenic patients according to degree of neuropsychological dysfunction. At least three different neuropsychological subtypes of schizophrenia were found. Memory, specifically delayed recall, was the most important factor that discriminated the groups. Neuropsychological assessment, covering a range of functional domains of the major dimensions of behavior, has an important role in identifying preserved and impaired capacities, in predicting outcome, and in planning treatment.

Keywords: Neuropsychology, Memory, Wisconsin Card Sorting Test, Schizophrenia

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PII: S0165-1781(04)00216-1

doi:10.1016/j.psychres.2003.08.017

Psychiatry Research
Volume 129, Issue 2 , Pages 191-199, 15 December 2004

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