Psychiatry Research
Volume 133, Issue 2 , Pages 277-280 , 28 February 2005

Lack of extrapyramidal side effects predicts quality of life in outpatients treated with clozapine or with typical antipsychotics

  • Sergio A. Strejilevich

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Ana Palatnik

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Rubén Avila

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Julián Bustin

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Julieta Cassone

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Soledad Figueroa

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Mariana Gimenez

      Affiliations

    • Servicio de Psicopatología, Hospital General de Agudos Parmenio Piñero, Av. Varela 1301, Buenos Aires, Argentina
  • ,
  • Gabriel A. de Erausquin

      Affiliations

    • Departments of Psychiatry and Neurology, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8134, St Louis, MO 63110, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 314 362 5186; fax: +1 314 747 2983.

Received 7 January 2004 ,Revised 22 October 2004 ,Accepted 25 October 2004.

References 

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  3. Cramer J, Rosenheck R, Xu W, Henderson W, Thomas J, Charney D Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Detecting improvement in quality of life and symptomatology in schizophrenia. Schizophrenia Bulletin. 2001;27:227–234
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  7. Modestin J, Stephan PL, Erni T, Umari T. Prevalence of extrapyramidal syndromes in psychiatric inpatients and the relationship of clozapine treatment to tardive dyskinesia. Schizophrenia Research. 2000;42:223–230
  8. Simpson GM, Josiassen RC, Stanilla JK, de Leon J, Nair C, Abraham G, et al. Double-blind study of clozapine dose response in chronic schizophrenia. American Journal of Psychiatry. 1999;156:1744–1750
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  10. Strejilevich S, Palatnik A, Avila R, Bustin J, Cassone J, Figueroa S, et al. Do resistant schizophrenic patients with clozapine improve more than non-resistant patients with typical antipsychotics?. European Psychiatry. 2004;19(Suppl. 1):174S
  11. Tauscher J, Kapur S. Choosing the right dose of antipsychotics in schizophrenia: lessons from neuroimaging studies. CNS Drugs. 2001;15:671–678
  12. Wahlbeck K, Cheine M, Essali A, Adams C. Evidence of clozapine's effectiveness in schizophrenia: a systematic review and meta-analysis of randomized trials. American Journal of Psychiatry. 1999;156:990–999
  13. Wolff AL, O'Driscoll GA. Motor deficits and schizophrenia: the evidence from neuroleptic-naive patients and populations at risk. Journal of Psychiatry and Neuroscience. 1999;24:304–314

PII: S0165-1781(04)00270-7

doi: 10.1016/j.psychres.2004.10.009

Psychiatry Research
Volume 133, Issue 2 , Pages 277-280 , 28 February 2005