Psychiatry Research
Volume 133, Issue 2 , Pages 129-133, 28 February 2005

A comparison of electronic monitoring vs. clinician rating of antipsychotic adherence in outpatients with schizophrenia

Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA

Received 29 June 2004; received in revised form 31 August 2004; accepted 8 November 2004.

Abstract 

Antipsychotic non-adherence rates of outpatients with schizophrenia or schizoaffective disorder was assessed by electronic monitoring and clinician rating. Antipsychotic adherence was determined monthly over 3 consecutive months with (1) the Medication Event Monitoring System (MEMS®) cap and (2) the Clinician Rating Scale. Non-adherence was defined as daily adherence of <70% during any one of three monthly evaluations for MEMS® and ratings of ≤4 (scale of 1–7) on the Clinician Rating Scale. Non-adherence was detected in 12 of 25 patients (48%) by MEMS® and 0% by the Clinician Rating Scale. Clinician assessment dramatically underestimated antipsychotic non-adherence.

Keywords: Antipsychotic adherence and non-adherence, Electronic monitoring, Clinician rating

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PII: S0165-1781(04)00290-2

doi:10.1016/j.psychres.2004.11.002

Psychiatry Research
Volume 133, Issue 2 , Pages 129-133, 28 February 2005