Psychiatry Research
Volume 137, Issue 3 , Pages 215-221 , 15 December 2005

Dermatoglyphic anomalies and neurocognitive deficits in sibling pairs discordant for schizophrenia spectrum disorders

  • Araceli Rosa

      Affiliations

    • Unitat d'Antropologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 645, 08028 Barcelona, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34 93 402 14 61.
  • ,
  • Manuel J. Cuesta

      Affiliations

    • Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea s/n, 31008 Pamplona, Spain
  • ,
  • Víctor Peralta

      Affiliations

    • Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea s/n, 31008 Pamplona, Spain
  • ,
  • Amalia Zarzuela

      Affiliations

    • Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea s/n, 31008 Pamplona, Spain
  • ,
  • Fermín Serrano

      Affiliations

    • Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea s/n, 31008 Pamplona, Spain
  • ,
  • Alfredo Martínez-Larrea

      Affiliations

    • Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea s/n, 31008 Pamplona, Spain
  • ,
  • Lourdes Fañanás

      Affiliations

    • Unitat d'Antropologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 645, 08028 Barcelona, Spain

Received 23 January 2003 ,Revised 19 September 2004 ,Accepted 20 July 2005.

References 

  1. Babler WJ. Embryologic development of epidermal ridges and their configurations. Birth Defects Original Articles Series. 1991;27:95–112
  2. Bracha HS, Torrey EF, Bigelow LB, Lohr JB, Linington BB. Subtle signs of prenatal maldevelopment of the hand ectoderm in schizophrenia: a preliminary monozygotic twin study. Biological Psychiatry. 1991;30:719–725
  3. Cannon TD, Zorrilla LE, Shtasel D, Gur RE, Gur RC, Marco EJ, et al. Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers. Archives of General Psychiatry. 1994;51:651–661
  4. Clouston TS. The Neuroses of Development. Edinburgh: Oliver and Boyd; 1891;
  5. Cornblatt B. Continuous Performance Test-Identical Pairs Version: Bio Behavioural Technologies Inc.. 1996;
  6. Cuesta MJ, Peralta V, Zarzuela A. Illness duration and neuropsychological impairments in schizophrenia. Schizophrenia Research. 1998;33:141–150
  7. Davis JO, Bracha HS. Prenatal growth markers in schizophrenia: a monozygotic co-twin control study. American Journal of Psychiatry. 1996;153:1166–1172
  8. Fañanás L, Moral P, Bertranpetit J. Quantitative dermatoglyphics in schizophrenia: study of family history subgroups. Human Biology. 1990;62:421–427
  9. Fañanás L, van Os J, Hoyos C, McGrath J, Mellor CS, Murray R. Dermatoglyphic a–b ridge count as a possible marker for developmental disturbance in schizophrenia: replication in two samples. Schizophrenia Research. 1996;20:307–314
  10. Fearon P, Lane A, Airie M, Scannell J, McGowan A, Byrne M, et al. Is reduced dermatoglyphic a–b ridge count a reliable marker of developmental impairment in schizophrenia?. Schizophrenia Research. 2001;50:151–157
  11. Goldberg TE, Weinberger DR, Berman KF, Pliskin NH, Podd MH. Further evidence for dementia of the prefrontal type in schizophrenia? A controlled study of teaching the Wisconsin Card Sorting Test. Archives of General Psychiatry. 1987;44:1008–1014
  12. Goldberg TE, Torrey EF, Gold JM, Bigelow LB, Ragland RD, Taylor E, et al. Genetic risk of neuropsychological impairment in schizophrenia: a study of monozygotic twins discordant and concordant for the disorder. Schizophrenia Research. 1995;17:77–84
  13. Green MF, Satz P, Gaier DJ, Ganzell S, Kharabi F. Minor physical anomalies in schizophrenia. Schizophrenia Bulletin. 1989;15:91–99
  14. Green MF, Bracha HS, Satz P, Christenson CD. Preliminary evidence for an association between minor physical anomalies and second trimester neurodevelopment in schizophrenia. Psychiatry Research. 1994;53:119–127
  15. Heaton R. Wisconsin Card Sorting Test Manual. Odessa, FL: Psychological Assessment Resources, Inc.; 1993;
  16. Kremen WS, Seidman LJ, Pepple JR, Lyons MJ, Tsuang MT, Faraone SV. Neuropsychological risk indicators for schizophrenia: a review of family studies. Schizophrenia Bulletin. 1994;20:103–119
  17. Loranger AW, Sartorius N, Andreoli A, Berger P, Buchheim P, Channabasavanna SM, et al. The International Personality-Disorder examination — the World-Health-Organization-Alcohol, Drug-Abuse, and Mental-Health Administration International Pilot-Study of Personality-Disorders. Archives of General Psychiatry. 1994;51:215–224
  18. Markow TA, Wandler K. Fluctuating dermatoglyphic asymmetry and the genetics of liability to schizophrenia. Psychiatry Research. 1986;19:323–328
  19. Murray RM, Lewis SW. Is schizophrenia a neurodevelopmental disorder?. British Medical Journal. 1987;295:681–682
  20. O'Callaghan E, Larkin C, Kinsella A, Waddington JL. Familial, obstetric, and other clinical correlates of minor physical anomalies in schizophrenia. American Journal of Psychiatry. 1991;148:479–483
  21. Rakic P. Specification of cerebral cortical areas. Science. 1988;241:170–176
  22. Reitan R. Validity of the Trail Making Test as an indicator of organic brain damage. Perceptual and Motor Skills. 1958;8:271–276
  23. Rosa A, Fañanás L, Bracha HS, Torrey EF, van Os J. Congenital dermatoglyphic malformations and psychosis: a twin study. American Journal of Psychiatry. 2000;157:1511–1513
  24. Rosa A, Gutiérrez B, Guerra A, Arias B, Fañanás L. Dermatoglyphics and abnormal palmar flexion creases as markers of early prenatal stress in children with idiopathic intellectual disability. Journal of Intellectual Disability Research. 2001;45:416–423
  25. Rosa A, Fañanás L, van Os J, Ribchester T, Davies N, Arias B, et al. Further evidence that congenital dermatoglyphic abnormalities are associated with psychosis: a twin study. Schizophrenia Bulletin. 2002;28:697–701
  26. Saoud M, d'Amato T, Gutknecht C, Triboulet P, Bertaud JP, Marie-Cardine M, et al. Neuropsychological deficit in siblings discordant for schizophrenia. Schizophrenia Bulletin. 2000;26:893–902
  27. Staal WG, Hijman R, Hulshoff Pol HE, Kahn RS. Neuropsychological dysfunctions in siblings discordant for schizophrenia. Psychiatry Research. 2000;95:227–235
  28. Suddath RL, Christison GW, Torrey EF, Casanova MF, Weinberger DR. Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia. New England Journal of Medicine. 1990;322:789–794
  29. Turek S. Dermatoglyphics and schizophrenia: analysis of quantitative traits. Collegium Anthropologicum. 1990;14:137–150
  30. van Oel CJ, Baare WF, Hulshoff Pol HE, Haag J, Balazs J, Dingemans A, et al. Differentiating between low and high susceptibility to schizophrenia in twins: the significance of dermatoglyphic indices in relation to other determinants of brain development. Schizophrenia Research. 2001;52:181–193
  31. van Os J, Fañanás L, Cannon M, Macdonald A, Murray R. Dermatoglyphic abnormalities in psychosis: a twin study. Biological Psychiatry. 1997;41:624–626
  32. Weickert TW, Goldberg TE, Gold JM, Bigelow LB, Egan MF, Weinberger DR. Cognitive impairments in patients with schizophrenia displaying preserved and compromised intellect. Archives of General Psychiatry. 2000;57:907–913
  33. Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Archives of General Psychiatry. 1987;44:660–669
  34. Weinberger DR, Berman KF, Suddath R, Torrey EF. Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. American Journal of Psychiatry. 1992;149:890–897

PII: S0165-1781(05)00210-6

doi: 10.1016/j.psychres.2005.07.006

Psychiatry Research
Volume 137, Issue 3 , Pages 215-221 , 15 December 2005