Psychiatry Research
Volume 169, Issue 2 , Pages 139-143 , 30 September 2009

Clinical symptoms of major depression are associated with the intensity dependence of auditory event-related potential components

  • Thomas Linka

      Affiliations

    • Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg-Essen, 45147 Essen, Germany
    • Vincent van Gogh Institute for Psychiatry, Postbus 5, 5800 AA Venray, The Netherlands
    • Corresponding Author InformationCorresponding author. Clinic for Psychiatry and Psychotherapy, University of Duisburg-Essen, Virchowstrasse 174, 45147 Essen, Germany. Tel.: +49 201 7227 226; fax: +49 201 7227 303.
    • ,
  • Gudrun Sartory

      Affiliations

    • Department of Clinical Psychology, University of Wuppertal, 42097 Wuppertal, Germany
    • ,
  • Markus Gastpar

      Affiliations

    • Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg-Essen, 45147 Essen, Germany
    • ,
  • Norbert Scherbaum

      Affiliations

    • Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg-Essen, 45147 Essen, Germany
    • Clinic for Addictive Behavior and Addiction Medicine, Rheinische Kliniken Essen, University of Duisburg-Essen, 45147 Essen, Germany
    • ,
  • Bernhard W. Müller

      Affiliations

    • Clinic for Psychiatry and Psychotherapy, Rheinische Kliniken Essen, University of Duisburg-Essen, 45147 Essen, Germany
    • Clinic for Addictive Behavior and Addiction Medicine, Rheinische Kliniken Essen, University of Duisburg-Essen, 45147 Essen, Germany

Received 3 June 2007 ,Revised 1 January 2008 ,Accepted 12 June 2008.

References 

  1. American Psychiatry Association, 1994. Diagnostic and statistical manual of mental disorders, 4th Edn. Apa, Washington, DC.
  2. Bonato, R. (Ed.), 1976. CGI. Glinical Global Impressions. In: Manual for the EDCEU Assessment Battery, vol. 12, 2nd ed. NIMH, Chevy Chase, MD.
  3. Beauducel A, Debener S, Brocke B, Kayser J. On the reliability of augmenting/reducing. Peak amplitudes and principal component analysis of auditory evoked potentials. Journal of Psychophysiology. 2000;14:226–240
  4. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Archives of General Psychiatry. 1961;4:561–571
  5. Brocke, B., Beauducel, A., John, R., Debener, S., Heilemann, H., 2000. Sensation seeking and affective disorders: characteristics in the intensity dependence of acoustic evoked potentials. Neuropsychobiology 41 (1), 24–30.
  6. Buchsbaum M, Silverman J. Stimulus intensity control and the cortical evoked response. Psychosomatic Medicine. 1968;30:12–22
  7. Carrillo-de-la-Pena MT, Mavrogiorgou P, Juckel G, Hauke W, Gallinat J, Frodl T, et al. Loudness dependence of auditory evoked potentials in obsessive–compulsive disorder: a pilot study. Psychiatry Research. 2000;93:209–216
  8. Clayton AH, Zajecka J, Ferguson JM, Filipiak-Reisner JK, Brown MT, Schwartz GE. Lack of sexual dysfunction with the selective noradrenaline reuptake inhibitor reboxetine during treatment for major depressive disorder. International Clinical Psychopharmacology. 2003;18:151–156
  9. Croft RJ, Klugman A, Baldeweg T, Gruzelier JH. Electrophysiological evidence of serotonergic impairment in long-term MDMA (“ecstasy”) users. American Journal of Psychiatry. 2001;158:1687–1692
  10. Cyranowski JM, Frank E, Cherry C, Houck P, Kupfer DJ. Prospective assessment of sexual function in women treated for recurrent major depression. Journal of Psychiatric Research. 2004;38:267–273
  11. Debener S, Strobel A, Kurschner K, Kranczioch C, Hebenstreit J, Maercker A, et al. Is auditory evoked potential augmenting/reducing affected by acute tryptophan depletion?. Biological Psychology. 2002;59:121–133
  12. Fava M. Daytime sleepiness and insomnia as correlates of depression. Journal of Clinical Psychiatry. 2004;65(Suppl 16):27–32
  13. Fava M, Rosenbaum JF, Hoog SL, Tepner RG, Kopp JB, Nilsson ME. Fluoxetine versus sertraline and paroxetine in major depression: tolerability and efficacy in anxious depression. Journal of Affective Disorders. 2000;59:119–126
  14. Ferguson JM. SSRI antidepressant medications: adverse effects and tolerability. Primary Care Companion to the Journal of Clinical Psychiatry. 2001;3:22–27
  15. Gallinat J, Bottlender R, Juckel G, Munke-Puchner A, Stotz G, Kuss HJ, et al. The loudness dependency of the auditory evoked N1/P2-component as a predictor of the acute SSRI response in depression. Psychopharmacology (Berl). 2000;148:404–411
  16. Guy W. In: ECDEU Assessment Manual for Psychopharmacology, US Department of Health and Human Services Rockville, MD. 1976;p. 194–198
  17. Hamilton M. A rating scale for depression. Journal of Neurology, Neurosurgery and Psychiatry. 1960;23:56–62
  18. Harvey BH, Bouwer CD. Neuropharmacology of paradoxic weight gain with selective serotonin reuptake inhibitors. Clinical Neuropharmacology. 2000;23:90–97
  19. Hegerl U, Bottlender R, Gallinat J, Kuss HJ, Ackenheil M, Moller HJ. The serotonin syndrome scale: first results on validity. European Archives of Psychiatry and Clinical Neuroscience. 1998;248:96–103
  20. Hegerl U, Gallinat J, Juckel G. Event-related potentials. Do they reflect central serotonergic neurotransmission and do they predict clinical response to serotonin agonists?. Journal of Affective Disorders. 2001;62:93–100
  21. Hensch T, Wargelius HL, Herold U, Lesch KP, Oreland L, Brocke B. Further evidence for an association of 5-HTTLPR with intensity dependence of auditory-evoked potentials. Neuropsychopharmacology. 2006;31:2047–2054
  22. Juckel G, Hegerl U, Molnar M, Csepe V, Karmos G. Auditory evoked potentials reflect serotonergic neuronal activity—a study in behaving cats administered drugs acting on 5-HT1A autoreceptors in the dorsal raphe nucleus. Neuropsychopharmacology. 1999;21:710–716
  23. Juckel G, Gallinat J, Riedel M, Sokullu S, Schulz C, Moller HJ, et al. Serotonergic dysfunction in schizophrenia assessed by the loudness dependence measure of primary auditory cortex evoked activity. Schizophrenia Research. 2003;64:115–124
  24. Juckel G, Hegerl U, Giegling I, Mavrogiorgou P, Wutzler A, Schuhmacher C, et al. Association of 5-HT1B receptor polymorphisms with the loudness dependence of auditory evoked potentials in a community-based sample of healthy volunteers. American Journal of Medical Genetics B Neuropsychiatric Genetics. 2009;147B(4):454–458
  25. Juckel G, Pogarell O, Augustin H, Mulert C, Muller-Siecheneder F, Frodl T, et al. Differential prediction of first clinical response to serotonergic and noradrenergic antidepressants using the loudness dependence of auditory evoked potentials in patients with major depressive disorder. Journal Clinical Psychiatry. 2007;68:1206–1212
  26. Linka T, Müller BW, Bender S, Sartory G. The intensity dependence of the auditory evoked N1 component as a predictor of response to Citalopram treatment in patients with major depression. Neuroscience Letters. 2004;367:375–378
  27. Linka T, Müller BW, Bender S, Sartory G, Gastpar M. The intensity dependence of auditory evoked ERP components predicts responsiveness to reboxetine treatment in major depression. Pharmacopsychiatry. 2005;38:139–143
  28. Mulert, C., Juckel, G., Augustin, H., Hegerl, U., 2002. Comparison between the analysis of the loudness dependency of the auditory N1/P2 component with LORETA and dipole source analysis in the prediction of treatment response to the selective serotonin reuptake inhibitor citalopram in major depression. Clinical Neurophysiology 113 (10), 1566–1572.
  29. Norra C, Mrazek M, Tuchtenhagen F, Gobbele R, Buchner H, Sass H, et al. Enhanced intensity dependence as a marker of low serotonergic neurotransmission in borderline personality disorder. Journal of Psychiatric Research. 2003;37:23–33
  30. Owens MJ. Selectivity of antidepressants: from the monoamine hypothesis of depression to the SSRI revolution and beyond. Journal of Clinical Psychiatry. 2004;65(Suppl 4):5–10
  31. Paige SR, Fitzpatrick DF, Kline JP, Balogh SE, Hendricks SE. Event-related potential amplitude/intensity slopes predict response to antidepressants. Neuropsychobiology. 1994;30:197–201
  32. Perry PJ. Pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants. Journal of Affective Disorders. 1996;39:1–6
  33. Proietti-Cecchini A, Afra J, Schoenen J. Intensity dependence of the cortical auditory evoked potentials as a surrogate marker of central nervous system serotonin transmission in man: demonstration of a central effect for the 5HT1B/1D agonist zolmitriptan (311C90, Zomig). Cephalalgia. 1997;17:849–854discussion 799
  34. Sandor PS, Roon KI, Ferrari MD, van Dijk JG, Schoenen J. Repeatability of the intensity dependence of cortical auditory evoked potentials in the assessment of cortical information processing. Cephalalgia. 1999;19:873–879
  35. Semlitsch HV, Anderer P, Schuster P, Presslich O. A solution for reliable and valid reduction of ocular artifacts, applied to the P300 ERP. Psychophysiology. 1986;23:695–703
  36. Senkowski D, Linden M, Zubragel D, Bar T, Gallinat J. Evidence for disturbed cortical signal processing and altered serotonergic neurotransmission in generalized anxiety disorder. Biological Psychiatry. 2003;53:304–314
  37. Spielberger CD. Manual for the State-Trait-Anxiety Inventory. Palo Alto, CA: Consulting Psychologist Press; 1970;
  38. Strobel A, Debener S, Schmidt D, Hunnerkopf R, Lesch KP, Brocke B. Allelic variation in serotonin transporter function associated with the intensity dependence of the auditory evoked potential. American Journal of Medical Genetics. 2003;118B:41–47
  39. Tuchtenhagen F, Daumann J, Norra C, Gobbele R, Becker S, Pelz S, et al. High intensity dependence of auditory evoked dipole source activity indicates decreased serotonergic activity in abstinent ecstasy (MDMA) users. Neuropsychopharmacology. 2000;22:608–617
  40. von Knorring L, Perris C. Biochemistry of the augmenting-reducing response in visual evoked potentials. Neuropsychobiology. 1981;7:1–8
  41. Wang W, Wang Y, Fu X, Liu J, He C, Dong Y, et al. Cerebral information processing in personality disorders: I. Intensity dependence of auditory evoked potentials. Psychiatry Research. 2006;141:173–183
  42. Zuckerman M, Murtaugh T. Sensation seeking and cotrical augmenting-reducing. Psychophysiology. 1974;11:535–542

PII: S0165-1781(08)00176-5

doi: 10.1016/j.psychres.2008.06.009

Psychiatry Research
Volume 169, Issue 2 , Pages 139-143 , 30 September 2009

Article Tools

* Image Usage & Resolution