Psychiatry Research
Volume 179, Issue 2 , Pages 121-125 , 30 September 2010

Sex-different association of DAO with schizophrenia in Koreans

  • Byungsu Kim

      Affiliations

    • Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    • ,
  • Hyunsook Kim

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Republic of Korea
    • ,
  • Yeon Ho Joo

      Affiliations

    • Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    • ,
  • Jiyoung Lim

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Republic of Korea
    • ,
  • Chang-Yoon Kim

      Affiliations

    • Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    • ,
  • Kyuyoung Song

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, Republic of Korea
    • Corresponding Author InformationCorresponding author. Department of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Poongnap-dong, Songpa-gu, Seoul, 138-736, Republic of Korea. Tel.: +82 2 3010 4277; fax: +82 2 3010 4248.

Received 19 November 2007 ,Revised 29 July 2008 ,Accepted 25 August 2008.

References 

  1. Addington AM, Gornick M, Sporn AL, Gogtay N, Greenstein D, Lenane M, et al. Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified. Biological Psychiatry. 2004;55:976–980
  2. Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H, et al. Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 2002;99:13675–13680
  3. Chung S, Jung J, Chung HY, Yoo HK, Kim CY, Joo YH, et al. No association between polymorphisms of DAO and DAOA genes and homicidal behaviors in Korean schizophrenia. Psychiatric Genetics. 2007;17:313
  4. Corvin A, Donohoe G, McGhee K, Murphy K, Kenny N, Schwaiger S, et al. d-amino acid oxidase (DAO) genotype and mood symptomatology in schizophrenia. Neuroscience Letters. 2007;426:97–100
  5. Detera-Wadleigh SD, McMahon FJ. G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis. Biological Psychiatry. 2006;60:106–114
  6. Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA, et al. Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case–parent trios. American Journal of Human Genetics. 2005;77:918–936
  7. Fogel WA. Diamine oxidase (DAO) and female sex hormones. Agents and Actions. 1986;18:44–45
  8. Goldberg TE, Straub RE, Callicott JH, Hariri A, Mattay VS, Bigelow L, et al. The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology. 2006;31:2022–2032
  9. Hong CJ, Hou SJ, Yen FC, Liou YJ, Tsai SJ. Family-based association study between G72/G30 genetic polymorphism and schizophrenia. Neuroreport. 2006;17:1067–1069
  10. Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. American Journal of Psychiatry. 1991;148:1301–1308
  11. Jotova I, Pavlov V, Dimitrov O, Bachrach U. Developmental aspects of polyamine-oxidizing enzyme activities in the mouse kidney. Effects of testosterone. Amino Acids. 1999;17:267–276
  12. Jotova I, Wang C, Tabib A, Dimitrov O, Bachrach U. Effects of testosterone and 17, beta-estradiol on the polyamine metabolism in cultivated normal rat kidney epithelial cells. Amino Acids. 2000;18:353–361
  13. Kapoor R, Lim KS, Cheng A, Garrick T, Kapoor V. Preliminary evidence for a link between schizophrenia and NMDA-glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1). Brain Research. 2006;1106:205–210
  14. Ko YH, Joe SH, Cho W, Park JH, Lee JJ, Jung IK, et al. Estrogen, cognitive function and negative symptoms in female schizophrenia. Neuropsychobiology. 2006;53:169–175
  15. Konno R, Yasumura Y. Mouse mutant deficient in d-amino acid oxidase activity. Genetics. 1983;103:277–285
  16. Lee SG, Joo Y, Kim B, Chung S, Kim HL, Lee I, et al. Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans. Human Genetics. 2005;116:319–328
  17. Liu X, He G, Wang X, Chen Q, Qian X, Lin W, et al. Association of DAAO with schizophrenia in the Chinese population. Neuroscience Letters. 2004;369:228–233
  18. Liu YL, Fann CS, Liu CM, Chang CC, Wu JY, Hung SI, et al. No association of G72 and d-amino acid oxidase genes with schizophrenia. Schizophrenia Research. 2006;87:15–20
  19. Miller RF. d-serine as a glial modulator of nerve cells. Glia. 2004;47:275–283
  20. Mothet JP, Parent AT, Wolosker H, Brady RO, Linden DJ, Ferris CD, et al. d-serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America. 2000;97:4926–4931
  21. Rao ML, Kolsch H. Effects of estrogen on brain development and neuroprotection—implications for negative symptoms in schizophrenia. Psychoneuroendocrinology. 2003;28:83–96
  22. Salem JE, Kring AM. The role of gender differences in the reduction of etiologic heterogeneity in schizophrenia. Clinical Psychology Review. 1998;18:795–819
  23. Schell MJ. The N-methyl d-aspartate receptor glycine site and d-serine metabolism: an evolutionary perspective. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 2004;359:943–964
  24. Schumacher J, Jamra RA, Freudenberg J, Becker T, Ohlraun S, Otte AC, et al. Examination of G72 and d-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder. Molecular Psychiatry. 2004;9:203–207
  25. Wake K, Yamazaki H, Hanzawa S, Konno R, Sakio H, Niwa A, et al. Exaggerated responses to chronic nociceptive stimuli and enhancement of N-methyl-d-aspartate receptor-mediated synaptic transmission in mutant mice lacking d-amino-acid oxidase. Neuroscience Letters. 2001;297:25–28
  26. Wood LS, Pickering EH, Dechairo BM. Significant support for DAO as a schizophrenia susceptibility locus: examination of five genes putatively associated with schizophrenia. Biological Psychiatry. 2006;
  27. Yamada K, Ohnishi T, Hashimoto K, Ohba H, Iwayama-Shigeno Y, Toyoshima M, et al. Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and d-serine levels. Biological Psychiatry. 2005;57:1493–1503
  28. Yue W, Kang G, Zhang Y, Qu M, Tang F, Han Y, et al. Association of DAOA polymorphisms with schizophrenia and clinical symptoms or therapeutic effects. Neuroscience Letters. 2007;416:96–100

PII: S0165-1781(08)00270-9

doi: 10.1016/j.psychres.2008.08.009

Psychiatry Research
Volume 179, Issue 2 , Pages 121-125 , 30 September 2010

Article Tools