Psychiatry Research
Volume 169, Issue 2 , Pages 97-100 , 30 September 2009

Association between changes on the Negative Symptom Assessment scale (NSA-16) and measures of functional outcome in schizophrenia

  • Dawn I. Velligan

      Affiliations

    • University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MS 7797, San Antonio, TX 78229-3900, USA
    • Corresponding Author InformationCorresponding author. UTHSCSA Dept. of Psychiatry, MS 7797, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. Tel.: +1 210 567 5508; fax: +1 210 567 1291.
    • ,
  • Larry Alphs

      Affiliations

    • Ortho-McNeil Janssen, Titusville, NJ, USA
    • ,
  • Scott Lancaster

      Affiliations

    • Ortho-McNeil Janssen, Titusville, NJ, USA
    • ,
  • Robert Morlock

      Affiliations

    • Ortho-McNeil Janssen, Titusville, NJ, USA
    • ,
  • Jim Mintz

      Affiliations

    • University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MS 7797, San Antonio, TX 78229-3900, USA

Received 18 December 2007 ,Accepted 13 October 2008.

References 

  1. Alphs L, Summerfelt A, Lann H, Muller RJ. The Negative Symptom Assessment: a new instrument to assess negative symptoms of schizophrenia. Psychopharmacology Bulletin. 1989;25:159–163
  2. American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders. Washington, D.C.: APA; 1994;
  3. Anthony W, Blanch A. Supported employment for persons who are psychiatrically disabled: an historical and conceptual perspective. Psychosocial Rehabilitation Journal. 1987;11:5–23
  4. Arango C, Buchanan RW, Kirkpatrick B, Carpenter WT. The deficit syndrome in schizophrenia: implications for the treatment of negative symptoms. European Psychiatry. 2004;19:21–26
  5. Axelrod BN, Goldman RS, Alphs LD. Validation of the 16-item negative symptom assessment. Journal of Psychiatric Research. 1993;7:253–258
  6. Bellack AS, Mueser KT, Gingerich S, Agresta J. Social Skills Training for Schizophrenia: A Step-by-Step Guide. second ed.. New York: The Guilford Press; 2004;
  7. Bow-Thomas CC, Velligan DI, Miller AL, Olsen J. Predicting quality of life from symptomatology in schizophrenia at exacerbation and stabilization. Psychiatry Research. 1999;86:131–142
  8. Breier A, Schreiber JL, Dyer J, Pickar D. National Institute of Mental Health longitudinal study of chronic schizophrenia. Archives of General Psychiatry. 1991;48:239–246
  9. Campbell DT, Kenny DA. A Primer on Regression Artifacts. Guilford Publications, New York; 1999;
  10. Cronbach LJ, Furby L. How should we measure “change” — or should we?. Psychological Bulletin. 1970;74:68–80
  11. Dombrowski SB, Kane M, Tuttle NB, Kincaid W. Functional Needs Assessment Program for Chronic Psychiatric Patients. Tucson, AZ: Communication Skill Builders; 1990;
  12. Finkel SE. Causal Analysis with Panel Data. Sage Publications, Inc., Los Angeles; 1995;
  13. Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia?. American Journal of Psychiatry. 1996;153:321–330
  14. Green MF, Nuechterlein KH, Kern RS, Baade LE, Fenton WS, Gold JM, et al. Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study. American Journal of Psychiatry. 2008;165:221–228
  15. Heinrichs DW, Hanlon TE, Carpenter William T. The Quality of Life Scale: an instrument for rating the schizophrenic deficit syndrome. Schizophrenia Bulletin. 1984;10:388–398
  16. Ho B, Nopoulos P, Flaum M, Arndt S, Andreasen NC. Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life. American Journal of Psychiatry. 1998;155:1196–1201
  17. Jaeger J, Berns SM, Czobor P. The multidimensional scale of independent functioning: a new instrument for measuring functional disability in psychiatric populations. Schizophrenia Bulletin. 2003;29:153–168
  18. Kenny DA. Correlation and Causality. New York: John Wiley & Sons; 1979;
  19. McGurk SR, Mueser KT. Cognitive functioning, symptoms, and work in supported employment: a review and heuristic model. Schizophrenia Research. 2004;70:147–173
  20. McKibbin CL, Brekke JS, Sires D, Jeste DV, Patterson TL. Direct assessment of functional abilities: relevance to persons with schizophrenia. Schizophrenia Research. 2004;72:53–56
  21. Milev P, Ho BC, Arndt S, Andreasen NC. Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. American Journal of Psychiatry. 2005;162:495–506
  22. Mueser KT, Bellack AS, Morrison RL, Wixted JT. Social competence in schizophrenia: premorbid adjustment, social skill, and domains of functioning. Journal of Psychiatric Research. 1990;24:51–63
  23. Mueser KT, Becker DR, Wolfe R. Supported employment, job preferences, and job tenure and satisfaction. Journal of Mental Health. 2001;10:411–417
  24. Puig O, Penades R, Gasto C, Catalan R, Torres A, Salamero M. Verbal memory, negative symptomatology and prediction of psychosocial functioning in schizophrenia. Psychiatry Research. 2008;158:11–17
  25. Sharma T, Antonova L. Cognitive function in schizophrenia. Deficits, functional consequences, and future treatment. Psychiatric Clinics of North America. 2003;26:25–40
  26. Souêtre E. Economic evaluation in schizophrenia. Neuropsychobiology. 1997;35:67–69
  27. Trauer T, Duckmanton RA, Chiu E. Estimation of costs of public psychiatric treatment. Psychiatric Services. 1998;49:440–442
  28. Velligan DI, Mahurin RK, Diamond PM, Hazleton BC, Eckert SL, Miller AL. The functional significance of symptomatology and cognitive function in schizophrenia. Schizophrenia Research. 1997;25:21–31
  29. Velligan DI, Prihoda TJ, Dennehy EB, Biggs MM, Shores-Wilson K, Crismon MlL, et al. The Brief Psychiatric Rating Scale expanded version: how do new items affect factor structure?. Psychiatry Research. 2005;135:217–228
  30. Ventura J, Green MF, Shaner A, Liberman RP. Training and quality assurance with the Brief Psychiatric Rating Scale: ‘The drift busters’. International Journal of Methods in Psychiatric Research. 1993;3:221–244
  31. Wyatt RJ, Hantler I, Leary MC, Taylor E. An economic evaluation of schizophrenia. Social Psychiatry and Psychiatric Epidemiology. 1995;30:196–205

PII: S0165-1781(08)00358-2

doi: 10.1016/j.psychres.2008.10.009

Psychiatry Research
Volume 169, Issue 2 , Pages 97-100 , 30 September 2009

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