Psychiatry Research
Volume 169, Issue 2 , Pages 164-166, 30 September 2009

No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample

Section of Clinical Pharmacology, Department of Neurosciences “B.B. Brodie”, University of Cagliari, P.O. San Giovanni di Dio, Via Ospedale 46, 09124 Cagliari, Italy

Received 11 March 2008; received in revised form 18 November 2008; accepted 17 December 2008.

Abstract 

Polymorphisms within the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes are being studied for association with lithium prophylaxis in a sample of 155 Sardinian unrelated probands affected by bipolar disorder (BP). No significant association was shown between the polymorphisms of the genes studied and response to lithium treatment.

Keywords: Bipolar disorder, Lithium response, Isolated population

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PII: S0165-1781(08)00439-3

doi:10.1016/j.psychres.2008.12.004

Psychiatry Research
Volume 169, Issue 2 , Pages 164-166, 30 September 2009

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